NIH

NIH SBIR 2026 · SBIR · Phase II

PA-26-178 · Bioelectronic Medicine Devices for Chronic Conditions

Closed-loop bioelectronic and neuromodulation devices for chronic disease, advancing from Phase I feasibility to a clinical-grade prototype.

Closes Sep 5, 2026 Tech volume ≤ 6–12 pg Agency portal

Typical administrative requirements11 requirements · confirm against the solicitation

Page limitsNIH NOFO / SF424 (R&R)MECHANICAL

Technical volume ≤ 6–12 pg

Cover sheet, cost volume and commercialization material are typically excluded from the count — confirm exclusions in the live solicitation.

6–12 pg

FontNIH NOFO / SF424 (R&R)MECHANICAL

≥ 11 pt, no compression

Use a standard serif/sans face; condensed or narrow variants are commonly disallowed.

≥ 11 pt

MarginsNIH NOFO / SF424 (R&R)MECHANICAL

≥ 0.5″ on all four sides

Margins are measured from the PDF page box and usually include headers and footers.

≥ 0.5″

Line spacingNIH NOFO / SF424 (R&R)MECHANICAL

Single-spacing minimum

No more restrictive than single; tables and figures are typically exempt.

Single+

Required sectionsNIH NOFO / SF424 (R&R)SEMANTIC

All mandated technical sections present

Match the solicitation's required structure and headings exactly — a mismatched heading is a known reject trigger.

Required

EligibilityNIH NOFO / SF424 (R&R)SEMANTIC

US small business, < 500 employees

>50% US-owned and controlled by individuals; for SBIR the PI's primary employment must be with the firm at award.

SBC

Foreign ownershipNIH NOFO / SF424 (R&R)SEMANTIC

FOCI / foreign-affiliation disclosure

Disclose foreign ownership, control or influence and the foreign affiliations of key personnel where required.

Disclose

RegistrationsNIH NOFO / SF424 (R&R)SEMANTIC

SAM.gov + UEI active; SBC registry

Active SAM.gov registration and a valid Unique Entity ID at submission; SBA Company Registry for SBIR/STTR.

Active

Cost volumeNIH NOFO / SF424 (R&R)SEMANTIC

Separate cost volume within the topic ceiling

Submitted separately from the technical volume and within the program/topic funding ceiling.

Separate

AI-use disclosureNIH NOFO / SF424 (R&R)SEMANTIC

Disclose assistive AI use

Generative AI may typically assist with editing/formatting only; substantive content must be human-authored and any use disclosed where required.

If used

DeadlineNIH NOFO / SF424 (R&R)MECHANICAL

Submit via the agency portal by Sep 5, 2026

The full electronic submission, including every volume, must be certified before the closing date/time.

Sep 5

AI-use disclosure · NIH

SolicitFit checks compliance — it never writes your proposal.

Confirm this agency's AI-use policy in the current solicitation. Generative AI may typically assist with editing and formatting only; substantive content must be human-authored and any use disclosed where required.

The next step

Check your draft against PA-26-178

Paste this solicitation or upload the agency PDF to get the cited requirements matrix — then upload your draft for a line-item compliance report.

Run a free checkNo login · 2 / day

SolicitFit audits your human-written draft for administrative compliance. It does not write proposal content and is not legal advice or a guarantee of acceptance. Don't upload classified / ITAR / CUI material.